Table 3.
tTG | DGP | |||||
---|---|---|---|---|---|---|
Number of patients | Positive (n = 10) |
Negative (n = 100) |
p value* | Positive (n = 11) |
Negative (n = 99) |
p value* |
Median age, year (range) | 47.5 (19–82) | 47.8 (25–68) | 0.958 | 42.0 (19–82) | 48.1 (24–68) | 0.950 |
Mean disease duration (year) | 12.8 | 9.3 | 0.462 | 11.0 | 9.6 | 0.586 |
Localization of the disease (n) | 0.798 | 0.887 | ||||
Pancolitis | 5 | 50 | 0.533 | 6 | 50 | 0.526 |
Left-sided colitis | 3 | 37 | 0.420 | 3 | 34 | 0.458 |
Proctitis | 2 | 13 | 0.408 | 2 | 15 | 0.534 |
Medication (n) | 0.084 | 0.279 | ||||
Immunomodulators** | 5 | 27 | 0.089 | 5 | 29 | 0.221 |
Corticosteroid | 5 | 35 | 0.271 | 5 | 38 | 0.441 |
Mayo score | 6.40 ± 1.80 | 2.60 ± 1.70 | <0.01 | 6.10 ± 1.9 | 2.58 ± 1.94 | <0.01 |
Laboratory values | ||||||
Albumin (g/dl) | 4.15 ± 0.36 | 4.21 ± 0.48 | 0.987 | 4.15 ± 0.08 | 4.14 ± 0.60 | 0.950 |
Total cholesterol (mg/dl) | 173.1 ± 24.5 | 180.0 ± 30.7 | 0.358 | 163.4 ± 20.3 | 179.7 ± 31.1 | 0.03 |
Hemoglobin (g/dl) | 12.6 ± 1.52 | 13.8 ± 2.30 | 0.107 | 13.1 ± 1.63 | 13.5 ± 1.75 | 0.953 |
CRP (mg/dl) | 0.30 ± 0.31 | 0.19 ± 1.49 | 0.131 | 0.27 ± 0.25 | 0.20 ± 1.51 | 0.145 |
tTG serum tissue trans glutaminase (IgA), DGP serum deamidated gliadin peptide (IgA), CRP C-reactive protein
* Statistical comparison between sero-positive and sero-negative
** Azathioprine, 6-mercaptopurine, calcineurin inhibitor (tacrolimus) and anti-TNF agents