Table 4.
Relation between the positivity of celiac disease-specific antibodies, IBD-specific antibodies, and food-related antibodies
| Crohn’s disease | Ulcerative colitis | |||||
|---|---|---|---|---|---|---|
| Celiac serology Number of patients |
Positive* (n = 15) |
Negative** (n = 47) |
p value*** | Positive* | Negative** | p value*** |
| (n = 16) | (n = 94) | |||||
| Positive IBD-specific antibodies, n (%) | ||||||
| ASCA IgA/IgG | 8 (53.5) | 29 (61.7) | 0.57 | 2 (12.5) | 17 (18.1) | 0.59 |
| p-ANCA | 0 | 0 | 1 (6.25) | 5 (5.3) | 0.57 | |
| Positive food-related antibodies, n (%) | ||||||
| Wheat IgE | 2 (13.3) | 0 (0) | 0.01 | 1 (6.25) | 0 (0) | 0.08 |
| Milk IgG | 13 (86.6) | 30 (63.8) | 0.09 | 12 (75) | 62 (65.9) | 0.57 |
| Egg IgG | 15 (100) | 30 (63.8) | 0.10 | 8 (50.0) | 40 (41.7) | 0.43 |
| Wheat IgG | 9 (60) | 19 (40.4) | 0.189 | 1 (6.3) | 4 (4.3) | 0.67 |
| Pork IgG | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
ASCA anti-Saccharomyces cervisiae antibody, p-ANCA perinuclear anti-neutrophil cytoplasmic antibody
* Positive for either tTG or DGP
** Negative for both tTG and DGP
*** Statistical comparison between sero-positive and sero-negative