Table 3.

Factors associated with risk of gastroduodenal erosion

Factor	Unadjusted OR	p value	Adjusted OR	p value
Age ≥65 years	0.82 (0.64–1.05)	0.1210	0.83 (0.64–1.09)	0.1768
Men	1.23 (0.94–1.61)	0.1290	1.25 (0.93–1.70)	0.1413
Current tobacco smoking	0.69 (0.45–1.04)	0.0857	0.65 (0.41–1.01)	0.0597
Alcohol use	1.19 (0.94–1.50)	0.1497	1.14 (0.87–1.48)	0.3447
Diabetes mellitus	1.30 (1.00–1.67)	0.0465	1.06 (0.69–1.60)	0.7917
H. pylori antibody positive	0.38 (0.29–0.48)	<0.0001	0.34 (0.26–0.44)	<0.0001
History of peptic ulcer	0.94 (0.70–1.25)	0.6599	1.05 (0.77–1.43)	0.7597
Enteric-coated aspirin	0.47 (0.33–0.67)	<0.0001	0.47 (0.32–0.70)	0.0002
Proton pump inhibitor	0.44 (0.32–0.61)	<0.0001	0.32 (0.22–0.46)	<0.0001
H2-receptor antagonist	0.60 (0.44–0.81)	0.0010	0.49 (0.36–0.68)	<0.0001
Cytoprotective antiulcer drug	1.12 (0.82–1.51)	0.4776	1.01 (0.72–1.39)	0.9592
Angiotensin II receptor blocker	1.12 (0.88–1.42)	0.3496	1.21 (0.94–1.56)	0.1339
HMG-Co A reductase inhibitor	1.03 (0.81–1.30)	0.8159	1.05 (0.82–1.35)	0.6838
Antidiabetic drug	1.34 (1.00–1.78)	0.0484	1.27 (0.79–2.05)	0.3289

Factors associated with gastroduodenal injuries suggestive in Table 1, with significant difference and established for gastroduodenal injuries according to previous studies, were examined for risk of gastroduodenal erosion using data of 1330 participants excluding those without H. pylori information and with ulcer. Risk of gastroduodenal erosion was estimated by the odds ratio with 95 % confidential interval using a monovariate (“Unadjusted”) or multivariate (“Adjusted”, which adjusted by all listed variables) logistic regression model