Figure 1.

Structure of cilia. (a) Cilia are cellular organelles composed of microtubules, and they project from the apical surface of numerous cell types. (b) A cilium is composed of a membrane domain, a soluble compartment or cilioplasm, an axoneme and a basal body. The membrane domain contains multiple sensory and channel proteins, several of which play a role in calcium-mediated fluid-flow mechanosensation. (c) The orientation of the microtubules in the axoneme is categorized as “9+0” or “9+2” and is anchored to the basal body. Taken and adapted from [1].