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. 2014 Mar 13;4(1):47–62. doi: 10.3390/bios4010047

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Calcium response to fluid flow in ex vivo arteries. (a) Within ex vivo arteries, fluid flow causes an influx of calcium. (b) In tissues with knocked-down Pkd2, a ciliary calcium channel, or that are treated with apyrase, the response profile is changed. Tissues were incubated with a fluorescent calcium dye prior to perfusion. Change in cytosolic calcium was pseudocolored; white/green represents a low level of cytosolic calcium, and yellow/red denotes a higher level. Taken and adapted from [6].