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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Mol Cancer Ther. 2014 Mar 14;13(5):1130–1141. doi: 10.1158/1535-7163.MCT-13-0880

Table 1.

Effect of PKD Inhibitors on Cell Proliferation

Cell Lines PKD Inhibitor IC50 (μmol/L)
CRT0066101 kb-NB142-70 CID755673
RKO 0.90 ± 0.17 2.82 ± 0.67 24.68 ± 5.50
HCT116 (p53+/+) 0.77 ± 0.25 2.69 ± 0.07 15.51 ± 2.55
HCT116 (p53−/−) 1.01 ± 0.06 3.08 ± 0.38 17.52 ± 1.80
H630 1.28 ± 0.18 4.33 ± 2.18 46.7 ± 27.65
H630R1 1.56 ± 0.34 8.35 ± 4.31 35.28 ± 5.42

IC50 values represent the concentration of drug that suppressed cell growth by 50%.

Values represent the mean ± S.D. from 3–5 determinations.