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. Author manuscript; available in PMC: 2014 May 14.

Published in final edited form as: Clin Cancer Res. 2009 Nov 10;15(22):7085–7091. doi: 10.1158/1078-0432.CCR-09-0822

Table 3.

Treatment-emergent adverse events reported in at least 20% of patients

Adverse event	All patients (N = 29)
Adverse event	Grade 1 n (%)	Grade 2 n (%)	Grade 3 n (%)	Grade 4 n (%)	All Grades n (%)
Any	4 (14)	11 (38)	11 (38)	3 (10)	29 (100)
Fatigue	10 (35)	3 (10)	1 (3)	0 (0)	14 (48)
Nausea	11 (38)	3 (10)	0 (0)	0 (0)	14 (48)
Diarrhea	7 (24)	3 (10)	0 (0)	0 (0)	10 (35)
Cough	8 (28)	0 (0)	0 (0)	0 (0)	8 (28)
Dyspnea	6 (21)	0 (0)	1 (3)	1 (3)	8 (28)
Hypoesthesia	5 (17)	3 (10)	0 (0)	0 (0)	8 (28)
Pyrexia	5 (17)	3 (10)	0 (0)	0 (0)	8 (28)
Headache	7 (24)	0 (0)	0 (0)	0 (0)	7 (24)
Peripheral edema	7 (24)	0 (0)	0 (0)	0 (0)	7 (24)
Constipation	5 (17)	1 (3)	0 (0)	0 (0)	6 (21)
Exertional dyspnea	6 (21)	0 (0)	0 (0)	0 (0)	6 (21)
Paresthesia	4 (14)	2 (7)	0 (0)	0 (0)	6 (21)