Table 1.

Estimates for the amplitudes and dissociation rate constants for transient molecules

		Analysis of transient molecules
		T1			T2			T3
DNA type	N	a1	kd,1, s−1	τ1, s	a2	kd,2, s−1	τ2, s	a3	kd,3, s−1	τ3, s
Undamaged DNA	307	0.79	1.22	0.8	0.39	1.23 × 10−1	8.1	0.07	8.85 × 10−3	113.0
Lower bound of 95% CI		0.76	1.13	0.8	0.37	1.07 × 10−1	7.2	0.05	4.50 × 10−3	75.8
Upper bound of 95% CI		0.81	1.31	0.9	0.41	1.40 × 10−1	9.3	0.09	1.32 × 10−2	222.1
Damaged DNA	436	1.11	3.03	0.3	0.25	1.25 × 10−1	8.0	0.21	7.89 × 10−3	126.7
Lower bound of 95% CI		1.03	2.78	0.3	0.24	1.09 × 10−1	7.1	0.20	7.13 × 10−3	115.4
Upper bound of 95% CI		1.19	3.28	0.4	0.27	1.41 × 10−1	9.2	0.22	8.66 × 10−3	140.4

N represents the total number of observed counts. a_i represent the coefficient of the exponential terms obtained from the fits. k_d,i represent the dissociation rate constants and τ_i represent the mean lifetimes. The lower and upper bounds corresponding to the 95% confidence intervals (CI) are presented for the population of transient molecules observed in this study.