Fig. 4.

Activation of L6 alters the relay of high-frequency sensory stimuli. VPM neurons were stimulated with 8-Hz whisker deflection trains (green bars) with and without L6 photoactivation (blue bars). (A, Upper) PSTH of a VPM neuron’s spiking response in control condition. (Lower) Response to the same stimulus during L6 photostimulation (blue bars) starting 200 ms before the whisker deflection train. (B) Population average of the probability of VPM spike responses (n = 10) for control trials (green trace) and during L6 stimulation (blue trace). Asterisks indicate response probabilities that were changed significantly by L6 activation (Methods).