Table 2. Reasons for inclusion of studies not meeting inclusion criteria.

Study	Reason for not fulfilling inclusion criteria	Reason for inclusion in the review
Leentjens et al. (2003)11	n < 20	Limited number of placebo-controlled studies available for the treatment of depression in PD
Avila et al. (2003)13	n < 20	Limited number of controlled studies available for the treatment of depression in PD
Lou et al. (2010)33	n < 20	Limited number of placebo-controlled studies using modafinil for the treatment of fatigue in PD available
Fernandez et al. (2009)63	n < 20	The only positive placebo-controlled study using quetiapine for the treatment of psychosis in PD
Tyne et al. (2010)34	n < 20	Limited number of placebo-controlled studies using modafinil for the treatment of fatigue in PD available
Thomas et al. (2010)39	n < 20	Limited number of placebo-controlled studies using amantadine for the treatment of pathological gambling in PD available; crossover study – power higher than in parallel group studies
Aarsland et al. (2002)42	n < 20	Limited number of placebo-controlled studies using donepezil for the treatment of dementia in PD available; crossover study – power higher than in parallel group studies
Leroi et al. (2004)44	n < 20	Limited number of placebo-controlled studies using donepezil for the treatment of dementia in PD available
Schoffer et al. (2007)67	n < 20	Limited number of studies available for the treatment of OH in PD
Hussain et al. (2001)69	n < 20; PD and MSA patients included	Limited number of studies available for the treatment of erectile dysfunction in PD; analysis given separately for MSA and PD patients
Thomsen et al. (2007)79	n < 20; study duration 2 weeks	Limited number of studies using anticholinergics available for the treatment of sialorrhea in PD; for endpoint sialorrhea 2-week study duration sufficient
Arbouw et al. (2010)80	Study duration 1 week	Limited number of studies using anticholinergics available for the treatment of sialorrhea in PD; for endpoint sialorrhea 1-week study duration sufficient
Ondo et al. (2004)84	n < 20	Limited number of placebo-controlled studies using BTX-B for the treatment of sialorrhea in PD available
Stocchi et al. (1998)88	Study duration 2 weeks	Limited number of studies using levodopa for the treatment of insomnia available
Adler et al. (2003)101	Study duration 3 weeks	Limited number of studies using modafinil for the treatment of EDS available
Hogl et al. (2002)99	n < 20	Limited number of placebo-controlled studies using modafinil for the treatment of EDS in PD available; crossover study – power higher than in parallel group studies

PD, Parkinson's disease; OH, orthostatic hypotension; MSA, multiple system atrophy; BTX-B, botulinum toxin B; EDS, excessive daytime somnolence.