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| Efficacy | Safety | Practice implications | |
|---|---|---|---|
| Clozapine | Efficacious | Acceptable risk with specialized monitoring | Clinically useful |
| Olanzapine | Unlikely efficacious | Unacceptable risk | Not useful |
| Quetiapine | Insufficient evidence | Acceptable risk without specialized monitoring | Investigational |
Treatments with new conclusions have gray backgrounds and italicized text, and those with no changes have white backgrounds.
PD, Parkinson's disease.
