Skip to main content
. Author manuscript; available in PMC: 2015 Apr 9.
Published in final edited form as: Cell Host Microbe. 2014 Apr 9;15(4):424–434. doi: 10.1016/j.chom.2014.03.005

Figure 5. Loss of FasL signaling leads to a dampened host cytokine response upon infection with Y. pestis Δpla.

Figure 5

At 48 h post-inoculation with the indicated bacterial strains, lungs were perfused and homogenized. Levels of IL-12p70, TNF, IFN-γ, MCP-1, and IL-6 were measured in lung homogenates by cytometric bead array. Cytokine levels are represented as fold change relative to mock infection values. n = 10 for all groups representing data combined from two independent experiments. “CFU load (48 h)” indicates the approximate numbers of bacteria in the lungs under each condition at the time of analysis. *P < 0.05, **P < 0.01, and ***P < 0.001; Student’s t test. See also Figure S5.