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. Author manuscript; available in PMC: 2015 Apr 9.
Published in final edited form as: Cell Host Microbe. 2014 Apr 9;15(4):413–423. doi: 10.1016/j.chom.2014.03.006

Figure 3.

Figure 3

PDC depletion abrogates PSA protection in a TNBS colitis model. PDC depletion by DT administration (200 ng/dose, 6 doses) to BDCA2-DTR mice before inflammation onset inhibits PSA-mediated protection. Boxplots show median (horizontal bar inside box) and quartile distributions in the TNBS model. Left and right panels show colitis scores with and without DT, respectively. Each dot in the boxplots represents an individual mouse. Scores were assessed for statistical significance by two-tailed nonparametric Mann-Whitney test. **p<0.01; ns, not significant. See also Figure S2.