Figure 2.

Twenty-four week risperidone treatment increased mice weight and food intake. (a) Effect of risperidone on weight gain in female mice. Differences between both groups appeared significant after 7 weeks of treatment and remained significant at the end of the experiment (24 weeks: control (∘) 24.58 ± 1.21 g versus risperidone (•) 31.33 ± 2.42 g; P < 0.01, n = 24). (b) Effect of risperidone on food intake. Risperidone treatment increased food intake after 13 weeks (Control: 3.90 ± 0.17 g/day/mouse versus Risperidone: 4.43 ± 0.47 g/day/mouse P < 0.05; n = 24).