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. 2013 May 28;4(4):334–343. doi: 10.1111/jdi.12075

Table 3. Metabolic syndrome and relative risk of type 2 diabetes mellitus.

References Year Definition Population n F/U (years) Adjusted RR or HR (95% CI)
Sattar et al.48 2003 Modified NCEP West of Scotland Coronary Prevention Study (male adults) 5,974 4.9 7.26 (2.25–23.4) in 3 components

24.4 (7.53–79.6) in 4 components

7.65 (5.99–9.31) in IFG components
Wilson et al.33 2005 NCEP Framingham Offspring study (middle‐aged adults) 3,323 8.0 11.0 (8.1–14.9) in metabolic syndrome including

IFG 5.0 (3.7–6.8) in metabolic syndrome excluding IFG
Wang et al.72 2007 WHO

EGIR

AACE

IDF

Modified NCEP
Beijing Project (part of the National Diabetes Survey Population) 541 5.0 2.39 (1.51–3.77)

1.88 (1.08–3.27)

2.97 (1.85–4.76)

2.05 (1.27–3.30)

2.33 (1.47–3.70)

2.61 (1.61–4.24) in IFG component
Cheung et al.40 2007 Modified NCEP

IDF
Hong Kong Cardiovascular Risk Factor Prevalence Study cohort 1,679 6.4 4.1 (2.8–6.0)

3.5 (2.3–5.2)

5.1 (3.0–8.7) in IFG components
Cameron et al.37 2007 WHO

EGIR

NCEP

IDF
A longitudinal survey in Mauritius 3,685 5.0 4.6 (3.5–6.0)

3.2 (2.3–4.3)

3.1 (2.3–4.0)

3.0 (2.2–4.2)

3.3 (2.6–4.3) in IFG component
Cameron et al.42 2008 WHO

EGIR

IDF

NCEP
Australian Diabetes, Obesity, and Lifestyle (AusDiab) study (adults, age ≥25 years) 5,842 5.0 7.8 (5.5–11.0)

7.4 (5.2–10.4)

5.5 (3.9–7.6)

6.4 (4.6–9.0)

3.05 in IFG component
Ley et al.36 2009 NCEP

IDF
Sandy Lake Health and Diabetes Project 492 10 2.03 (1.10–3.75)

2.14 (1.29–3.55)

2.30 (1.40–3.77) per 1 mmol/L increment of FPG
Salminen et al.51 2012 IDF Populations of Lieto in Finland (age ≥64 years) 1,117 9 3.15 (1.89–5.25)

5.16 (2.68–9.93)

in IFG component

CI, confidence interval; EGIR, European Group for the Study of Insulin Resistance; F/U, follow‐up period; FPG, fasting plasma glucose; HR, hazard ratio; IDF, International Diabetes Federation; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; NCEP, National Cholesterol Education Program; NHANES, National Health and Nutrition Examination Survey; RR, relative risks; WHO, World Health Organization.