Table 3. Metabolic syndrome and relative risk of type 2 diabetes mellitus.
References | Year | Definition | Population | n | F/U (years) | Adjusted RR or HR (95% CI) |
---|---|---|---|---|---|---|
Sattar et al.48 | 2003 | Modified NCEP | West of Scotland Coronary Prevention Study (male adults) | 5,974 | 4.9 |
7.26 (2.25–23.4) in 3 components 24.4 (7.53–79.6) in 4 components 7.65 (5.99–9.31) in IFG components |
Wilson et al.33 | 2005 | NCEP | Framingham Offspring study (middle‐aged adults) | 3,323 | 8.0 |
11.0 (8.1–14.9) in metabolic syndrome including IFG 5.0 (3.7–6.8) in metabolic syndrome excluding IFG |
Wang et al.72 | 2007 |
WHO EGIR AACE IDF Modified NCEP |
Beijing Project (part of the National Diabetes Survey Population) | 541 | 5.0 |
2.39 (1.51–3.77) 1.88 (1.08–3.27) 2.97 (1.85–4.76) 2.05 (1.27–3.30) 2.33 (1.47–3.70) 2.61 (1.61–4.24) in IFG component |
Cheung et al.40 | 2007 |
Modified NCEP IDF |
Hong Kong Cardiovascular Risk Factor Prevalence Study cohort | 1,679 | 6.4 |
4.1 (2.8–6.0) 3.5 (2.3–5.2) 5.1 (3.0–8.7) in IFG components |
Cameron et al.37 | 2007 |
WHO EGIR NCEP IDF |
A longitudinal survey in Mauritius | 3,685 | 5.0 |
4.6 (3.5–6.0) 3.2 (2.3–4.3) 3.1 (2.3–4.0) 3.0 (2.2–4.2) 3.3 (2.6–4.3) in IFG component |
Cameron et al.42 | 2008 |
WHO EGIR IDF NCEP |
Australian Diabetes, Obesity, and Lifestyle (AusDiab) study (adults, age ≥25 years) | 5,842 | 5.0 |
7.8 (5.5–11.0) 7.4 (5.2–10.4) 5.5 (3.9–7.6) 6.4 (4.6–9.0) 3.05 in IFG component |
Ley et al.36 | 2009 |
NCEP IDF |
Sandy Lake Health and Diabetes Project | 492 | 10 |
2.03 (1.10–3.75) 2.14 (1.29–3.55) 2.30 (1.40–3.77) per 1 mmol/L increment of FPG |
Salminen et al.51 | 2012 | IDF | Populations of Lieto in Finland (age ≥64 years) | 1,117 | 9 |
3.15 (1.89–5.25) 5.16 (2.68–9.93) in IFG component |
CI, confidence interval; EGIR, European Group for the Study of Insulin Resistance; F/U, follow‐up period; FPG, fasting plasma glucose; HR, hazard ratio; IDF, International Diabetes Federation; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; NCEP, National Cholesterol Education Program; NHANES, National Health and Nutrition Examination Survey; RR, relative risks; WHO, World Health Organization.