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. Author manuscript; available in PMC: 2014 May 14.
Published in final edited form as: Adv Exp Med Biol. 2010;695:155–168. doi: 10.1007/978-1-4419-7037-4_11

Figure 1.

Figure 1

Representation of a stem cell niche: the stem cell niche is the place where humoral, neuronal, local (paracrine), positional (physical) and metabolic cues interact with each other to regulate stem cell fate. (Adapted from Scadden DT. Nature 441:1075–1079).