Table 3.
Bacteriostatic and bactericidal characteristics of antibiotic solutions and experimental surfactant/antibacterial mixtures.
| Antibiotics and antibiotic/surfactant compositions | MIC and MBC data (mg/L) | |||||
|---|---|---|---|---|---|---|
| S. aureus | K. pneumoniae | P. aeruginosa | ||||
| MIC | MBC | MIC | MBC | MIC | MBC | |
| Amikacin | 3.9 | 3.9 | 1.9 | 1.9 | 3.9 | 3.9 |
| Amikacin + surfactant | 3.9 | 3.9 | 1.9 | 1.9 | 3.9 | 3.9 |
| Cefepime | ≤0.49 | 1.9 | >1,000 | >1,000 | 3.9 | 500 |
| Cefepime + surfactant | ≤0.49 | 3.9 | >1,000 | >1,000 | 3.9 (1.9) | 1,000 |
| Colistimethate sodium | 80 | 80 | 20 | 160 | 20 | 160 |
| Colistimethate sodium + surfactant | 20 | 80 | 20 (10) | 160 | 10 | 160 |
Notes: MBC: minimum bactericidal concentration; MIC: minimum inhibitory concentration. Additional MIC values are presented in round parentheses when different results were obtained for distinct replications.