Table 4.
Single and multiple type HPV infection status according to histopathological diagnoses
|
HPV type |
Type of infection |
CIN1 |
CIN2 or worse |
Glandular (AIS and CC) |
P1 |
P2 |
|---|---|---|---|---|---|---|
|
(n = 60) |
(n = 209) |
(n = 18) |
CIN 1 vs CIN 2 or worse | CIN 2 or worse vs glandular | ||
| N(%) | N(%) | N(%) | ||||
| hr-HPV |
|
|
|
|
|
|
| 16 |
Single |
6 (10) |
45 (22) |
10 (55) |
|
|
| |
Multiple |
13 (22) |
64 (31) |
4 (22) |
0.46 |
0.04 |
| 58 |
Single |
0 |
12 (6) |
0 |
|
|
| |
Multiple |
8 (13) |
24 (11) |
1 (5) |
0.08 |
1 |
| 52 |
Single |
0 |
9 (4) |
0 |
|
|
| |
Multiple |
5 (8) |
19 (9) |
1(5) |
0.29 |
1 |
| 31 |
Single |
4 (7) |
7 (3) |
0 |
|
|
| |
Multiple |
5 (8) |
16 (8) |
0 |
0.68 |
NC |
| 35 |
Single |
2 (3) |
4 (2) |
0 |
|
|
| |
Multiple |
7 (12) |
13 (6) |
1 (5) |
1 |
0.98 |
| 33 |
Single |
1 (<2) |
6 (3) |
0 |
|
|
| |
Multiple |
2 (3) |
17 (8) |
0 |
1 |
NC |
| 18 |
Single |
1 (<2) |
0 |
3 (17) |
|
|
| |
Multiple |
2 (3) |
3 (<2) |
4 (22) |
NC |
0.03 |
| 51 |
Single |
1 |
2 (1) |
0 |
|
|
| |
Multiple |
7 (12) |
10 (5) |
1 (5) |
1 |
1 |
| 45 |
Single |
0 |
3 (<2) |
0 |
|
|
| |
Multiple |
2 (3) |
8 (4) |
1 (5) |
1 |
NC |
| 56 |
Single |
0 |
2 (1) |
0 |
|
|
| |
Multiple |
3 (5) |
6 (3) |
0 |
1 |
NC |
| 39 |
Single |
1 (<2) |
1 (<1) |
0 |
|
|
| |
Multiple |
3 (5) |
5 (2) |
0 |
1 |
NC |
| Other |
Single |
6 (10) |
4 (2) |
0 |
|
|
| hr-HPV |
Multiple |
13 (22) |
34 (16) |
1 (5) |
0.07 |
1 |
| Any hr- |
Single |
22 (37) |
95 (45) |
13 (72) |
|
|
| HPV |
Multiple |
34 (57) |
110 (53) |
5 (28) |
0.36 |
<0.05 |
| lr-HPV |
|
|
|
|
|
|
| 6 |
Single |
2 (3) |
1 (<1) |
0 |
|
|
| |
Multiple |
2 (3) |
3 (<2) |
0 |
1 |
NC |
| 11 |
Single |
0 |
1 (<1) |
0 |
|
|
| |
Multiple |
0 |
0 |
0 |
NC |
NC |
| Others |
Single |
6 (10) |
4 (2) |
0 |
|
|
| lr-HPV |
Multiple |
15 (25) |
34 (16) |
1 (5) |
0.14 |
NC |
| Any HPV |
Single |
26 (43) |
99 (47) |
13 (72) |
|
|
| Multiple | 34 (57) | 110 (53) | 5 (28) | 0.66 | 0.04 | |
Prevalence was calculated by dividing the number of infected cases per HPV type by the number of women with the histopathological diagnosis. Totals surpass 100% because women with MT infections are counted at least twice. hr-HPV: high-risk HPV, lr-HPV: low-risk HPV, CIN: cervical intraepithelial neoplasia, AIS: in situ adenocarcinoma, CC: invasive cervical cancer.