Table 2. Single‐nucleotide polymorphism association with type 2 diabetes in the China National Diabetes and Metabolic Disorders Study by logistic regression analysis.
| SNP | Case | Control | ADD | REC | DOM | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AA | Aa | aa | MAF | AA | Aa | aa | MAF | OR (95% CI) | P a | OR (95% CI) | P a | OR (95% CI) | P a | |
| rs391300 | 2063 | 1754 | 347 | 0.29 | 2284 | 1840 | 354 | 0.29 | 0.98 (0.91 –1.06) | 0.74 | 1.04 (0.87 –1.25) | 0.63 | 0.96 (0.87 –1.06) | 0.49 |
| rs4523957 | 2156 | 1846 | 338 | 0.29 | 2384 | 1963 | 373 | 0.29 | 0.99 (0.92 –1.07) | 0.93 | 1.04 (0.87 –1.25) | 0.62 | 0.98 (0.89 –1.08) | 0.70 |
A, major allele; a, minor allele; ADD, genotypic additive; CI, confidence interval; DOM, genotypic dominant; MAF, minor allele frequency; OR, odds ratio; REC, genotypic recessive.
a
Adjusted for age, sex and body mass index.