Table 1. Baseline clinical characteristics and laboratory findings of study participants.
Characteristics | Control (n = 6,019) | Adenoma (n = 3,606) | P |
---|---|---|---|
Age (years) | 48.7 ± 9.4 | 53.3 ± 8.8 | <0.05 |
Sex, male (%) | 53.6 | 74.5 | <0.05 |
Familial history of CRC (%) | 4.5 | 4.2 | NS |
Current smoking (%) | 22.5 | 32.1 | <0.05 |
Alcohol (%) | 38.3 | 49.5 | <0.05 |
BMI (kg/m2) | 23.7 ± 2.9 | 24.6 ± 2.8 | <0.05 |
Waist circumference (cm) | 81.6 ± 8.8 | 85.3 ± 8.4 | <0.05 |
Male | 85.7 ± 7.4 | 87.4 ± 7.3 | <0.05 |
Female | 76.8 ± 7.7 | 79.4 ± 8.3 | <0.05 |
Total cholesterol (mg/dL) | 192.4 ± 33.4 | 195.5 ± 34.1 | <0.05 |
Triglyceride (mg/dL) | 114.7 ± 73.7 | 131.7 ± 82.2 | <0.05 |
HDL cholesterol (mg/dL) | 57.4 ± 14.3 | 54.7 ± 13.4 | <0.05 |
LDL cholesterol (mg/dL) | 123.9 ± 29.7 | 127.4 ± 29.8 | <0.05 |
Glucose (mg/dL) | 96.4 ± 13.2 | 99.6 ± 15.2 | <0.05 |
Serum insulin (μIU/mL) | 5.9 ± 3.6 | 6.5 ± 4.0 | <0.05 |
HOMA‐IR | 1.4 ± 1.1 | 1.6 ± 1.2 | <0.05 |
BMI, body mass index; CRC, colorectal cancer; HDL, high‐density lipoprotein; HOMA‐IR, homeostasis model assessment of insulin resistance; LDL, low‐density lipoprotein; NS, not significant.