Table 4. Odds ratios of colorectal adenoma according to quartiles of homeostasis model assessment of insulin resistance.
| HOMA‐IR (median) | OR (95% CI) | P for trends | |||
|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | ||
| <0.83 (0.57) | 0.83 –1.25 (1.05) | 1.25 –1.89 (1.54) | >1.89 (2.90) | ||
| Univariate | 1.0 (ref) | 1.25 (1.11–1.40)a | 1.17 (1.04–1.32)a | 1.63 (1.45–1.83)a | <0.05 |
| Model 1 | 1.0 (ref) | 1.18 (1.04–1.35)a | 1.10 (0.97–1.26) | 1.45 (1.28–1.65)a | <0.05 |
| Model 2 | 1.0 (ref) | 1.11 (0.97–1.27) | 0.99 (0.86–1.13) | 1.20 (1.04–1.38)a | NS (P = 0.07) |
a
P < 0.05. Model 1: Adjusted for age, sex, current smoking, alcohol drinking, family history of colorectal cancer. Model 2: Further adjusted for body mass index. CI, confidence interval; HOMA‐IR, homeostasis model assessment of insulin resistance; NS, not significant; OR, odds ratio; Q, quartile.