Table 1.
Disease category | ICD-9 code | ICD-9 description | Number (%) with both disorders | Association odds ratio | Association P value | Temporal P value |
---|---|---|---|---|---|---|
Endocrine, nutritional and metabolic diseases, and immunity disorders | 250.00* | Type 2 diabetes mellitus | 243 (62.6) | 55.4 | <5 × 10−324 | 8.5 × 10−37 |
278.00 | Obesity | 52 (13.4) | 11.7 | 2.4 × 10−95 | 4.1 × 10−4 | |
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Nervous system | 356.9 | Peripheral neuropathy | 161 (41.5) | 101.2 | <5 × 10−324 | 3.9 × 10−12 |
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Blood and blood-forming organs | 280.0 | Anemia due to chronic blood loss | 16 (4.1) | 9.9 | 1.0 × 10−26 | 0.80 |
285.9 | Anemia, not otherwise specified | 98 (25.3) | 14.9 | 3.3 × 10−205 | 0.085 | |
285.29 | Anemia of other chronic diseases | 10 (2.6) | 43.1 | 1.1 × 10−79 | 1 | |
280.9 | Iron deficiency anemia | 32 (8.2) | 14.5 | 1.5 × 10−79 | 0.60 | |
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Skin and subcutaneous tissue | 682.6 | Cellulitis/abscess of leg | 87 (22.4) | 41.9 | <5 × 10−324 | 4.4 × 10−6 |
682.7 | Cellulitis/abscess of foot | 98 (25.3) | 133.8 | <5 × 10−324 | 5.5 × 10−6 | |
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Genitourinary system | 593.9 | Renal & ureteral disorder, not otherwise specified | 119 (30.7) | 20.9 | <5 × 10−324 | 4.5 × 10−4 |
585 | Chronic kidney disease | 64 (16.5) | 29.4 | 7.7 × 10−314 | 2.4 × 10−5 | |
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Musculoskeletal system and connective tissue | 714.0 | Rheumatoid arthritis | 37 (9.5) | 13.5 | 1.2 × 10−83 | 1.3 × 10−5 |
733.00 | Osteoporosis | 44 (11.3) | 12.1 | 4.4 × 10−86 | 0.29 | |
733.90 | Bone/cartilage disorder, not otherwise specified | 233 (60.1) | 26.0 | <5 × 10−324 | 5.9 × 10−12 | |
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Injury and poisoning | 996.81 | Complication of kidney transplant | 44 (11.3) | 43.3 | <5 × 10−324 | 3.9 × 10−4 |
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External causes of injury and supplemental classification | V42.0 | Kidney transplant | 50 (12.9) | 42.1 | <5 × 10−324 | 9.0 × 10−5 |
*This table only lists ICD-9 code 250.00, not the other diabetes codes that also appeared in this cohort of patients.