Table 3.
Well-known associations with Charcot foot, compared between those with (n = 282) and without (n = 106) diabetes, defined as any ICD-9 250.x code. The associations shown here are based on the ones shown in Table 1.
| Disease category | ICD-9 code | ICD-9 description | Number (%) among those with diabetes | Number (%) among those without diabetes | P value for difference in proportions |
|---|---|---|---|---|---|
| Endocrine, nutritional and metabolic diseases, and immunity disorders | 278.00 | Obesity | 46 (16.3) | 6 (5.7) | 10.0 × 10−3 |
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| Nervous system | 356.9 | Peripheral neuropathy | 143 (50.7) | 18 (17.0) | 3.80 × 10−9 |
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| Blood and blood-forming organs | 280.0 | Anemia due to chronic blood loss | 14 (5.0) | 2 (1.9) | 0.28 |
| 285.9 | Anemia, not otherwise specified | 88 (31.2) | 10 (9.4) | 2.0 × 10−5 | |
| 285.29 | Anemia of other chronic diseases | 8 (2.8) | 2 (1.9) | 0.87 | |
| 280.9 | Iron deficiency anemia | 29 (10.3) | 3 (2.8) | 0.030 | |
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| Skin and subcutaneous tissue | 682.6 | Cellulitis/abscess of leg | 80 (28.4) | 7 (6.6) | 8.8 × 10−6 |
| 682.7 | Cellulitis/abscess of foot | 94 (33.3) | 4 (3.8) | 5.2 × 10−9 | |
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| Genitourinary system | 593.9 | Renal & ureteral disorder, not otherwise specified | 111 (39.4) | 8 (7.5) | 3.0 × 10−9 |
| 585 | Chronic kidney disease | 63 (22.3) | 1 (0.9) | 9.3 × 10−7 | |
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| Musculoskeletal system and connective tissue | 714.0 | Rheumatoid arthritis | 28 (9.9) | 9 (8.5) | 0.81 |
| 733.00 | Osteoporosis | 36 (12.8) | 8 (7.5) | 0.21 | |
| 733.90 | Bone/cartilage disorder, not otherwise specified | 175 (62.1) | 58 (54.7) | 0.23 | |
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| Injury and poisoning | 996.81 | Complication of kidney transplant | 43 (15.2) | 1 (0.9) | 1.6 × 10−4 |
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| External causes of injury and supplemental classification | V42.0 | Kidney transplant | 49 (17.4) | 1 (0.9) | 3.6 × 10−5 |