Table 2.
Mean difference in lung function and odds ratio for airflow obstruction per 10 pack years of smoking among men, stratified by race/ethnicity
| Non-Hispanic Whites |
African-Americans | Hispanics | Chinese-Americans | P-value for differences across self-reported race/ethnic groups [p-value after excluding Chinese-Americans] |
P-value for differences by principal components of ancestry [p-value excluding Chinese-Americans] |
|
|---|---|---|---|---|---|---|
| n. | 582 | 402 | 342 | 283 | ||
| FEV1/FVC difference (%), (95% CI) |
||||||
| Age-height- adjusted* |
−0.75 (−1.02, −0.48) |
−1.05 (−1.58, −0.52) |
−0.88 (−1.30, −0.23) |
−0.33 (−0.89, 0.23) |
0.29 | 0.03 |
| Multivariable† | −0.75 (−1.08, −0.43) |
−0.65 (−1.20, −0.10) |
−0.77 (−1.26, −0.29) |
−0.33 (−0.95, 0.28) |
0.65 | 0.10 |
|
| ||||||
| FEV1 difference (mL), (95% CI) |
||||||
| Age-height- adjusted* |
−55.0 (−71.6, −38.4) |
−50.5 (−77.9, −23.0) |
−53.6 (−78.2, −28.4) |
−17.0 (−45.9, 11.9) |
0.013 [0.84] |
0.004 [0.38] |
| Multivariable† | −42.7 (−61.7, −23.6) |
−32.1 (−61.2, −3.0) |
−44.2 (−73.4, −14.9) |
−25.5 (−56.4, 5.42) |
0.007 [0.26] |
0.007 [0.23] |
|
| ||||||
| Airflow obstruction OR (95% CI) |
||||||
| Age-height- adjusted* |
1.16 (1.06, 1.23) |
1.23 (1.06, 1.43) |
1.30 (1.11, 1.53) |
1.18 (0.92, 1.52) |
0.51 | 0.61 |
| Multivariable† | 1.20 (1.07, 1.35) |
1.17 (0.98, 1.40) |
1.38 (1.10, 1.73) |
1.41 (0.94, 2.11) |
0.43 | 0.67 |
*
Age-height-adjusted model adjusted for 10-pack-years of smoking, age, age2, height, height2, and current smoking status.
†
Multivariable model adjusted for 10 pack-years of smoking, age, age2, height, height2, body mass index, current smoking status, physician-diagnosed asthma before 45 years, family history of emphysema, cigar smoking status, cigar pack-years, second-hand smoke exposure, depth of inhalation, time before first cigarette in the morning, urinary cotinine level, history of hayfever, occupational exposure to dust, fumes or smoke, and educational attainment.