Table 2.
Management and in-hospital outcomes according to study period (1991–2010).
| Variables (%) | 1991–2000 | 2001–2010 |
P-value for trend |
|---|---|---|---|
| Medication during 1st 24 h of admission |
|||
| Thrombolytic | 1820 (71) | 2516 (65) | 0.001 |
| Antiplatelet drugs | 3122 (84) | 6822 (95) | 0.001 |
| Heparin | 2105 (56) | 4249 (59) | 0.003 |
| β-blockers | 1415 (38) | 4005 (56) | 0.001 |
| ACE inhibitors/ARB | 452 (12) | 2579 (36) | 0.001 |
| Coronary angiography | 1161 (31) | 1309 (18) | 0.001 |
| PCI | 95 (2.5) | 1051 (14.6) | 0.001 |
| CABG | 73 (2) | 140 (2) | 0.99 |
| In-hospital outcomes | |||
| Death | 329 (8.8) | 385 (5.4) | 0.001 |
| Cerebrovascular accident | 39 (1) | 11 (0.2) | 0.001 |
| Cardiogenic shock | 138 (3.7) | 207 (2.9) | 0.02 |
| Cardiac arrest | 266 (7.1) | 363 (5.1) | 0.001 |
| Congestive heart failure | 210 (5.6) | 252 (3.5) | 0.001 |
| Medication at discharge | |||
| Antiplatelet agent | 3318 (88.7) | 6931 (96.6) | 0.001 |
| β-blockers | 1415 (37.8) | 4005 (55.8) | 0.001 |
| ACE inhibitors/ARB | 452 (12.1) | 2579 (35.9) | 0.001 |
| Final discharge diagnosis | |||
| ST-elevation MI | 2547 (68) | 3859 (54) | |
| Non-ST-elevation MI | 1193 (32) | 3316 (46) | 0.001 |
| Hospital days (mean ± SD) | |||
| Coronary care units stay | 3 ± 1.7 | 3 ± 1.6 | 0.40 |
| Total hospital stay | 6.4 ± 3 | 4.6 ± 3 | 0.001 |
ACE inhibitors/ARB: angiotensin converting enzyme inhibitors/angiotensin receptor blocker; CABG: coronary artery bypass grafting; PCI: percutaneous coronary intervention; MI: myocardial infarction.