Table 6.
Overview of defined ANA patterns (modified from Wiik et al., 2010 [13]).
| Pattern group | Pattern |
|---|---|
| Nuclear envelope (membrane) |
Smooth nuclear envelope |
| Punctate nuclear envelope | |
|
| |
| Nuclear | Homogeneous pattern |
| Large speckled | |
| Coarse speckled | |
| Fine speckled | |
| Fine grainy Scl-70-like | |
| Pleomorphic speckled (i.e., PCNA) | |
| Centromere | |
| Multiple nuclear dots | |
| Coiled bodies (few nuclear dots) | |
| Dense fine speckled | |
| Isolated metaphase chromosomes | |
|
| |
| Nucleolar | Homogeneous nucleolar |
| Clumpy nucleolar | |
| Punctate nucleolar | |
|
| |
| Mitotic spindle apparatus |
Centriole (centrosome) |
| Spindle pole (NuMa) (MSA-1) (HSeg5) | |
| Spindle fiber | |
| Midbody (MSA-2) | |
| CENP-F (MSA-3) | |
|
| |
| Cytoplasmic | Diffuse |
| Fine speckled | |
| Mitochondrial | |
| Discrete dots: GW bodies, endosomes, lysosomes | |
| Golgi complex | |
| Intercellular contact proteins | |
| Fibers and cytoskeleton | |
| Rods and rings | |
|
| |
| Negative | |