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. 2014 Apr 28;2014:805801. doi: 10.1155/2014/805801

Table 2.

Characteristics of all studies assessing the relationship between VEGF and diabetic retinopathy (PDR versus NPDR).

First author Year Country/racial decent Study design Casesa (PDR) Controlsa (NPDR) Cases Controls
11b 12b 22b 11b 12b 22b
−634 G>C (rs2010963)
Awata [25] 2002 Japan (Asian) Hospital based controls 70 80 24 30 16 14 51 15
Uthra [19] 2008 India (Asian) Population based controls 44 87 21 17 3 39 33 7
Chun [21] 2010 Korea (Asian) Hospital based controls 145 108 48 73 24 37 52 19

+936 C/T (rs3025039)
Awata [25] 2002 Japan (Asian) Hospital based controls 70 80 44 20 6 49 27 4
Uthra [19] 2008 India (Asian) Population based controls 44 87 35 9 0 76 10 0
Kim [26] 2009 Korea (Asian) Population based controls 37 84 15 19 3 40 44 15

PDR: proliferative diabetic retinopathy; NPDR: nonproliferative diabetic retinopathy.

aSample size.

b11: wild-type homozygote; 12: heterozygote; 22: variant homozygote.