Table I.
Immunohistochemical and clinical characteristics of nine patients with esophageal carcinoma used for sequencing alternative polyadenylation sites and quantitative polymerase chain reaction analysis.
| Case # | Age/Gender | Neu | EGFR | TOPII | P53 | Ki67 (%) | PCNA | P21 | GST-π | c-myc | P27 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0a | 52/M | − | + | − | − | 5 | ++ | + | + | − | ++ |
| 1b | 66/M | − | − | − | − | 5 | + | − | + | − | − |
| 2b | 66/M | ++ | + | + | − | 20 | ++ | + | ++ | − | + |
| 3b | 65/M | ++ | − | − | ++ | 5 | ++ | − | + | − | − |
| 4b | 74/F | ++ | − | − | − | − | ++ | − | + | − | − |
| 6b | 59/F | + | + | − | − | 5 | ++ | − | + | − | − |
| 7b | 68/M | + | + | + | − | 20 | + | − | + | − | − |
| 14b | 72/F | − | − | − | ++ | 5 | ++ | − | + | − | + |
| 16b | 56/M | − | − | + | − | 30 | ++ | − | + | − | + |
a
Samples used for sequencing;
b
Samples used for qPCR analysis.
M, male; F, female; EGFR, epidermal growth factor receptor; Neu, neuro/glioblastoma derived oncogene homolog; TOPII, DNA topoisomerase II; PCNA, proliferating cell nuclear antigen; GST, glutathione S-transferase.