A, T2-weighted MRI images captured at the time of presentation
and B, six weeks later (three days prior to death).
C, Marked volume loss in the right cerebellar folia and
distortion of the medulla are likewise seen at the gross level.
D, Luxol fast blue (LFB) staining demonstrates marked
destruction and demyelination of the cerebellar white matter.
E, FLAIR and F, gadolinium-enhanced T1 MRI
three days prior to death demonstrates extensive subcortical and deep white
matter edema and contrast enhancement.