Table 2.
Cell line | IC50a | |
---|---|---|
Free Dox | DOX-loaded nanogelsb | |
A2780 | 0.024±0.012 | 0.725±0.079 |
MCF7 | 0.046±0.021 | 0.17±0.058 |
IC50 (μg/mL) represents the concentration of a drug for 50% inhibition in vitro (n=4).
DOX-loaded cl-PEG-b-PPGA nanogels with targeted degree of cross-linking of 20% were prepared at R = 0.5 and pH 7.0.