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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: J Drug Target. 2013 Sep 2;21(10):981–993. doi: 10.3109/1061186X.2013.831421

Table 2.

In vitro cytotoxicity of DOX-loaded cl-nanogels in cancer cells at 24h

Cell line IC50a
Free Dox DOX-loaded nanogelsb
A2780 0.024±0.012 0.725±0.079
MCF7 0.046±0.021 0.17±0.058
a

IC50 (μg/mL) represents the concentration of a drug for 50% inhibition in vitro (n=4).

b

DOX-loaded cl-PEG-b-PPGA nanogels with targeted degree of cross-linking of 20% were prepared at R = 0.5 and pH 7.0.