Table 4.
Analytical sensitivity of the three automated nucleic acid extraction systems.
| Virus strain dilution factor |
ADV-3 (detected/replicates) | FluA (detected/replicates) | RSV-A (detected/replicates) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 10−6 | 10−7 | 10−8 | 10−9 | 10−10 | 10−5 | 10−6 | 10−7 | 10−8 | 10−9 | 10−4 | 10−5 | 10−6 | 10−7 | 10−8 | |
| QIAcube (QIAGEN) | 5/5 | 3/5 | 0/5 | 0/5 | 0/5 | 5/5 | 2/5 | 1/5 | 0/5 | 0/5 | 5/5 | 4/5 | 0/5 | 0/5 | 0/5 |
| EZ1 (QIAGEN) | 5/5 | 5/5 | 0/5 | 0/5 | 0/5 | 5/5 | 5/5 | 2/5 | 1/5 | 0/5 | 5/5 | 5/5 | 3/5 | 1/5 | 0/5 |
| NIMBUS (Seegene) | 5/5 | 4/5 | 0/5 | 0/5 | 0/5 | 5/5 | 4/5 | 0/5 | 0/5 | 0/5 | 5/5 | 2/5 | 1/5 | 0/5 | 0/5 |