Table 1. Total and Partially Decomposed SASA of Fmoc-Dipeptidesa.
Fmoc-AA |
||||||
---|---|---|---|---|---|---|
total | Fmoc | Ala-mid-C=O | Ala-term-COOH | Ala-mid-NH | Ala-term-NH | |
nm2 | 165.3 | 58.5 | 9.2 | 33.1 | 1.4 | 2.5 |
percentage | 100.0 | 35.4 | 5.5 | 20.0 | 0.9 | 1.5 |
Fmoc-ALac |
||||||
---|---|---|---|---|---|---|
total | Fmoc | Ala-C=O (ester) | Lac-COOH | Ala-NH | Lac-O(ester) | |
nm2 | 155.7 | 55.9 | 8.1 | 37.5 | 1.9 | 1.1 |
percentage | 100.0 | 35.9 | 5.2 | 24.1 | 1.2 | 0.7 |
Ala-mid refers to the N-terminal alanine, and Ala-term refers to the C-terminal alanine. Percentages do not add up to 100% because the hydrophobic and hydrophilic groups of interest listed here do not comprise the entire surface area of the fibril.