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(A) Impact of Sti1 deletion upon Pop2 and Cbk1 ability to suppress Htt103Q toxicity. Growth assays were plated in 5-fold dilutions on glucose (−Htt) or galactose (+Htt). (B) Impact of Sti1 deletion upon Pop2 and Cbk1 ability to alter Htt103Q aggregation. Fluorescence microscopy was carried out as above, and nuclei were visualized using DAPI staining. (C) Model for Htt103Q benign aggregate assembly.
