Table 2. The comparisons of SCMBLP with some comparable methods using BLP-TRN in terms of 5- or 10-fold cross-validation accuracy (%).
Method | Classifier | Features | Optimization | Sensitivity | Specificity | Accuracy |
BLProt [6] | SVM | 100 PCPs | No | 74.47a | 84.21a | 80.00 |
PBLP [7] | SVM | 15 PCPs | Yes | 84.11 | 79.25 | 84.50 |
BLPre [8] | SVM | PSSM-AC | No | 79.33 | 91.00 | 85.17 |
SVM-Hybrid [9] | SVM | DPC+PSSM+RAAC+ACS | No | 88.33 | 92.67 | 90.50 |
SVM-DPC | SVM | DPC | No | 82.00 | 85.00 | 83.50 |
SCMBLP | SCM | DPC | Yes | 89.67 | 92.00 | 90.83 |
RAAC: Reduced amino acid composition;
ACS: Average chemical shift;
DPC: Dipeptide composition.
The results are test accuracies that the cross-validation accuracies were not reported.