Table 1. The characteristics of the studies included in the meta-analysis for the association of rs1883832 with atherosclerosis.
First author,Published year | Ethnicity | Controlsource | Studytype | Genotypingmethod | Diseasecategory | Case/Control | Male/female ratio | Mean age | ||
Case | Control | Case | Control | |||||||
Li Y, 2007* | Chinese | Population based | Replication | PCR-RFLP | ACS | 160/92 | 3.57 | 3.60 | 64.0 | 59.0 |
Wang CP, 2009* | Chinese | Patients angiographicallynormal | Replication | PCR-RFLP | CAD | 474/225 | 2.04 | 2.08 | 63.5 | 62.4 |
Tian CX, 2010* | Chinese | Population based | Replication | PCR-RFLP | ACS | 248/206 | 1.76 | 1.94 | 63.8 | 59.8 |
Yan JC, 2010* | Chinese | Population based | Replication | PCR-RFLP | ACS,SA | 399/163 | 3.53 | 3.41 | 63.8 | 62.8 |
Wang M,2011* | Chinese | Population based | Replication | PCR-RFLP | ACS | 160/180 | 3.57 | 3.62 | 64.4 | 60.7 |
Ma Y, 2013# | Chinese Han | Population based | Replication | PCR-RFLP | IS | 286/336 | 1.55 | 1.20 | 66.1 | 67.5 |
Zhang BK,2013# | Chinese Han | Population based | Replication | PCR-RFLP | CI | 402/693 | 2.14 | 1.14 | 63.2 | 50.5 |
Abbreviation: PCR-RFLP, polymerase chain reaction-restriction fragment length polymorphism; ACS, acute coronary syndrome; CAD coronary artery disease;
SA, stable angina; IS, ischemic stroke; CI, cerebral infarction.
Symbols: ‘*’ indicates the study on coronary artery disease; ‘#’ indicates the study on ischemic disease.