Table 3. Meta-analysis for the association of rs1883832 with atherosclerosis.
| Genetic model | OR 95% CI | P | P heterogeneity | I2 |
| C/C versus T/T | Crude OR1:1.926 (1.044, 3.555) | 0.036 | <0.001 | 88.5% |
| Modified OR1:1.896 (1.183, 3.041) | 0.008 | – | – | |
| C/T versus T/T | Crude OR2:1.502 (1.212, 1.862) | <0.001 | 0.183 | 32.1% |
| Modified OR2:1.474 (1.239, 1.753) | <0.001 | – | – | |
| C/C versus C/T | Crude OR3:1.214 (0.758, 1.942) | 0.42 | <0.001 | 87.7% |
| ModifiedOR3: 1.255(0.841, 1.873) | 0.265 | – | – | |
| Dominantmodel (C/C and C/T)versus T/T | OR4: 1.631(1.176, 2.260) | 0.003 | 0.001 | 72.5% |
| Recessive modelC/C versus (C/Tand T/T) | OR5: 1.370(0.821, 2.287) | 0.228 | <0.001 | 90.5% |
| Additive model | OR6: 1.361(0.981, 1.889) | 0.065 | <0.001 | 90.4% |
Included publications: CAD: Li Y, 2007; Wang CP, 2009; Tian CX, 2010; Yan JC, 2010; Wang M, 2011; IS or CI:
Ma Y, 2013; Zhang BK, 2013.
Likelihood ratio test: LR = 23.82, P<0.001.
Pooled C allele frequency: 46.8% (41.1%–52.5%), P heterogeneity<0.001, I2 = 91.5%.
Abbreviation: ACS, acute coronary syndrome; CAD coronary artery disease; IS, ischemic stroke; CI, cerebral infarction;
OR, odds ratio; 95% CI, 95% confidence interval.