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. 2014 May 14;9(5):e97289. doi: 10.1371/journal.pone.0097289

Table 4. Meta-analysis for the association of rs1883832 with coronary artery disease.

Genetic model OR 95%CI P P heterogeneity I2
C/C versus T/T Crude OR1: 2.869 (2.197, 3.746) <0.001 0.444 0%
Modified OR1: 2.866 (2.203, 3.729) <0.001
C/T versus T/T Crude OR2: 1.691 (1.359, 2.105) <0.001 0.838 0%
Modified OR2: 1.680 (1.352, 2.086) <0.001
C/C versus C/T Crude OR3: 1.688 (1.352, 2.109) <0.001 0.684 0%
Modified OR3: 1.707 (1.366, 2.132) <0.001
Dominant model (C/C and C/T) versus T/T OR4: 1.965 (1.594, 2.423) <0.001 0.58 0%
Recessive model C/C versus (C/T and T/T) OR5: 1.971 (1.594, 2.438) <0.001 0.603 0%
Additive model OR6: 1.689 (1.480, 1.927) <0.001 0.403 0.6%

Included publications: Li Y, 2007; Wang CP, 2009; Tian CX, 2010; Yan JC, 2010; Wang M, 2011.

Likelihood ratio test: LR = 63.73, P<0.001.

Pooled C allele frequency: 45.1% (42.7%–47.4%), P heterogeneity = 0.156, I2 = 39.7%.

Abbreviation: ACS, acute coronary syndrome; CAD coronary artery disease; IS, ischemic stroke; CI, cerebral infarction;

OR, odds ratio; 95% CI, 95% confidence interval.