Table 5. Meta-analysis for the association of rs1883832 with ischemic stroke.
| Genetic model | OR 95%CI | P | P heterogeneity | I2 |
| C/C versus T/T | Crude OR1: 0.684 (0.506, 0.926) | 0.014 | 0.933 | 0% |
| Modified OR1: 0.666 (0.477, 0.930) | 0.017 | – | – | |
| C/T versus T/T | Crude OR2: 1.216 (0.749, 1.974) | 0.429 | 0.093 | 64.6% |
| Modified OR2: 1.190 (0.866, 1.635) | 0.283 | – | – | |
| C/C versus C/T | Crude OR3: 0.556 (0.341, 0.907) | 0.019 | 0.04 | 76.4% |
| Modified OR3: 0.562 (0.402, 0.787) | 0.001 | – | – | |
| Dominant model (C/C and C/T) versus T/T | OR4: 0.992 (0.691, 1.423) | 0.965 | 0.188 | 42.3% |
| Recessive model C/C versus (C/T and T/T) | OR5: 0.582 (0.393, 0.864) | 0.007 | 0.085 | 66.3% |
| Additive model | OR6: 0.785 (0.679, 0.909) | 0.001 | 0.550 | 0% |
Included publications: Ma Y, 2013; Zhang BK,2013.
Likelihood ratio test: LR = 22.04, P<0.001.
Pooled C allele frequency: 49.9% (31.9%–67.8%), P heterogeneity<0.001, I2 = 98.4%.
Abbreviation: IS, ischemic stroke; OR, odds ratio; 95%CI, 95% confidence interval.