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. 2014 May 14;9(5):e97407. doi: 10.1371/journal.pone.0097407

Figure 6. Delta-24-RGD-mediated presentation of TAA to CD8+ T cells depended on biosynthetic and proteasome activity.

Figure 6

Cells were infected with Delta-24-RGD as in Figure 5. Brefeldin A (BFA, 6 µg/ml), MG132 (1 µM) or Lactacystin (Lac, 10 µM) was added during the last 24 h of the experiment. After fixed with PFA, the cells were incubated with CD8+ cells for 18 h and then the T-cell activation was assessed by β-Glo assay. Relative data are represented as mean ± S.E.; n = 3. P<0.05 (Student's t-test, double sided).