Table 1. Demographic data on subjects recruited to measure MMP-8 levels in blood samples.

	IPF patients	Control subjects¶	P value
Number of subjects	73	25
Age (years)	68.7 (7.9)†	62.9 (10.4)	0.006
Gender (% male)	69.2	80.0	0.446
Caucasian (%)	96.8	96.0	0.642
Hispanic (%)	3.2	12.0	0.276
FVC (L)	2.65 (0.8)	N/A††
FVC (% predicted)	69.8 (18.3)	N/A
TLC (L)	4.0 (1.1)	N/A
TLC (% predicted)	67.5 (21.0)	N/A
DLCO (mL/min/mmHg)	13.3 (6.1)	N/A
DLCO (% predicted)	49.9 (18.7)	N/A
Smoking (pack years)	23.3 (14.1)	2.08 (8.2)	<0.001

^†Data shown are mean results (with SD in parentheses) in both groups for age, gender, forced vital capacity (FVC), FVC % predicted (% pred), total lung capacity (TLC), TLC % predicted, diffusing capacity of the lung for carbon monoxide (DLCO), DLCO % predicted, and smoking pack years.

^††N/A: not available.

^¶MMP-8 levels were measured in plasma samples from 21 of the 25 control subjects, MMP-8 levels were measured in leukocytes isolated from up to 7 of the 25 control subjects, and MMP-8 levels were measured in both plasma and leukocyte samples obtained from 3 of the 25 control subjects.