Table 3. Statistic analysis of survival of tumor bearing mice.
Treatment group | Median survival (d) | Mean survival (d) | Maximal survival (d) | P |
Control | 25 | 26.33±1.63 | 32 | - |
Free DOX(5 mg/kg) | 31 | 31.33±1.68 | 36 | 0.045a |
DOX-hyd-PEG-FA NPs (2.5 mg/kg) | 31 | 34.17±1.85 | 42 | 0.386b |
DOX-hyd-PEG-FA NPs (5 mg/kg) | 36 | 37.33±1.52 | 42 | 0.049b |
DOX-hyd-PEG-FA NPs (10 mg/kg) | 38 | 39.00±1.31 | 42 | 0.007b |
a-compared with control, b-compared with free DOX.