Table 1.
E2 and P Regulation of Inflammation-Associated Gene Expression
| Symbol | Description | Fold Change |
Known P and E Regulation |
||
|---|---|---|---|---|---|
| 5-d E | 5-d P | E | P | ||
| Ccl1 | Chemokine (C-C motif) ligand 1 | No change | 2.7 | ||
| Ccl20 | Chemokine (C-C motif) ligand 20 | No change | 4.5 | ||
| Ccl3 | Chemokine (C-C motif) ligand 3 | 2.1 | No change | ↓ (56) | |
| Ccl8 | Chemokine (C-C motif) ligand 8 | 5.4 | 3.3 | ↑ (70) | |
| Cx3cl1 | Chemokine (C-X3-C motif) ligand 1 | No change | 2.9 | ↑ (71) | |
| Cxcl15 | Chemokine (C-X-C motif) ligand 15 | 12 | 5.7 | ||
| Cxcl5 | Chemokine (C-X-C motif) ligand 5 | 3.1 | No change | ||
| Il17b | IL-17B | 8.6 | 8.9 | ||
| Il8rb | IL-8 receptor, β | No change | −3.0 | ||
| Tnf | TNF | No change | 2.4 | ||
| Areg | Amphiregulin | 24 | 31 | ↑ (10) | ↑ (10) |
| RANKL | Receptor activator of nuclear factor κ B ligand | No change | 630 | ↑ (6, 7) | |
| SAA1 | Serum amyloid A1 | 2.2 | 1.8 | ↑ (4) | |
Direction of known P and E regulation (↑ or ↓) and the reference; n = 3 control-treated mice, n = 3 E2-treated mice, n = 3 P-treated mice. P ≤ .05 for all genes listed.