. Author manuscript; available in PMC: 2014 May 14.

Published in final edited form as: Eur Respir J. 2010 Jul 15;37(3):523–531. doi: 10.1183/09031936.00021210

Table 6.

Association of Exhaled Nitric Oxide (FeNO) with New-Onset Asthma by Parental History of Asthma

	Parental History of Asthma
	No				Yes
Age-Specific Quartiles of FeNO at Baseline	Cases	Non- cases	HR^*	95% CI	Cases	Non- cases	HR^*	95% CI

Quartile 1	13	393	1		9	81	2.55	1.08–6.04
Quartile 2	19	408	1.66	0.82–3.39	9	61	3.97	1.67–9.41
Quartile 3	18	395	1.80	0.87–3.73	7	65	3.77	1.48–9.61
Quartile 4	36	380	3.18	1.66–6.08	8	77	2.17	0.88–5.34

			p_trend<0.001^†				p_trend=0.33^†

	P interaction<0.05^‡

HR=Hazard ratio, adjusted for race/ethnicity, lifetime wheeze and community with baseline strata for age and gender

^†

Trend tests conducted in stratified models

^‡

P-value based on the chi-square statistic using the likelihood ratio test to compare a model with base terms to a model containing the interaction term