Table 2. Antiretroviral therapy use and frequency of HHV-8 detected by PCR of oropharyngeal swabs.
Antiretroviral use | Subjects (n) | Sessions (n) | Proportion of swabs with HHV-8 detected (%) | Mean log10 copies (SD) |
---|---|---|---|---|
ART-naïve | 46 | 68 | 1231/ 3111 (39.6%) | 4.9 (1.2) |
Previous ART only | 20 | 28 | 314/ 1272 (24.7%) | 4.1 (1.0) |
Non-HAART ART | 9 | 12 | 228 / 661 (34.5%) | 4.5 (1.1) |
HAART, no PI | 32 | 56 | 671 / 2216 (30.3%) | 4.9 (1.2) |
HAART with any PI | 55 | 98 | 572 / 4348 (13.2%) | 4.4 (1.1) |
HAART with nelfinavir | 12 | 21 | 217 / 1139 (19.1%) | 4.9 (1.1) |
Total | 162 | 262 | 3,016 / 11,608 (26.0%) | 4.7 (1.2) |
Among sessions with ≥ 1 positive day
Abbreviations: HHV-8, human herpesvirus 8; ART, antiretroviral therapy; HAART, highly active ART; PI, protease inhibitor; SD, standard deviation