Table 3.
Associations between variables and frequency of HHV-8 detection in oropharyngeal swabs by PCR.
| Univariate | Multivariate | |||
|---|---|---|---|---|
|
|
||||
| Covariate | RR (95% CI) | p | RR (95% CI) | p |
| Antiretroviral use | ||||
| ART-naïve | ref | ref | ||
| Previous ARVs only | 0.6 (0.3, 1.1) | 0.117 | 0.6 (0.3, 1.0) | 0.061 |
| Current ART, not HAART | 0.9 (0.5, 1.7) | 0.781 | 0.8 (0.3, 2.0) | 0.593 |
| HAART, no PI | 0.7 (0.4, 1.3) | 0.279 | 0.6 (0.3, 1.1) | 0.088 |
| HAART with any PI | 0.2 (0.1, 0.5) | 0.002 | 0.2 (0.1, 0.4) | <0.001 |
| HAART with nelfinavir | 0.7 (0.2, 1.9) | 0.465 | 0.6 (0.2, 1.7) | 0.361 |
| CD4 count | ||||
| CD4 >= 200 | ref | |||
| CD4 < 200 | 0.9 (0.5, 1.5) | 0.663 | ||
| Kaposi sarcoma | ||||
| KS negative | ref | ref | ||
| KS positive | 2.5 (1.5, 4.1) | 0.001 | 3.5 (1.8, 6.9) | <0.001 |
| HIV plasma viral load | ||||
| <500 copies/mL | ref | |||
| 500 to 10K copies/mL | 1.9 (1.1, 3.1) | .017 | ||
| 10K to 100K copies/mL | 1.3 (0.6, 2.7) | .513 | ||
| >100K copies/mL | 1.0 (0.6, 1.7) | .943 | ||
| Decades since HIV dx | 0.6 (0.4, 1.0) | .077 | ||
| Year of participation | 1.0 (0.9, 1.0) | .260 | ||
Multivariate models are adjusted for all of the variables listed.