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AS101 suppresses pro-inflammatory cytokine expression and elevates anti-inflammatory cytokine expression in the spinal cords during EAE. (A – C) Relative mRNA expression of: the pro-inflammatory cytokines IL-6, TNF-α and IL1-β (A): the chemokines MCP-1, iNOS and RANTES (B); and the anti-inflammatory cytokines Arginase-1 and IL-10 (C) in the spinal cord tissue of mice in the indicated groups at 14 days after immunization (6 mice per group). *p<0.01.
