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AS101 suppresses the migration of VLA-4 positive cells into the spinal cord in EAE mice. Quantification of brain infiltrates by flow cytometry. Spinal cord mononuclear cells from SHAM, EAE PBS-treated mice and EAE AS101-treated mice (n = 5––10 per group) were isolated on day 14 post immunization and subjected to flow cytometric analysis for VLA-4 in CD11b+ (A) and CD11b+Ly6C+Ly6G cells (B). *p<0.05.
