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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Neuromolecular Med. 2013 Nov 23;16(2):292–307. doi: 10.1007/s12017-013-8277-3

Figure 7.

Figure 7

AS101 prevents CD4+ cell migration in the EAE model. Histopathological assessment of EAE mice. Spinal cords (n = 5–10 per group) were removed on days 7, 14 and 21 post immunization. (A) The spinal cord sections were removed on day 14 post immunization from sham, PBS and AS101 groups and were stained with Hematoxylin and Eosin. Bar = 500 µm. (B) Representative images showing CD4 immunoreactivity in spinal cord sections from mice in the indicated groups (post-immunization day 14). Bar = 100 µm. (C) Results of quantitative analysis of CD4 cell staining (percentage of total spinal cord section area that exhibited CD4 immunoreactivity). **p<0.01 versus sham; ##p < 0.01 versus sham; †p < 0.05, ††p < 0.01 versus PBS value at the same time point).