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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Neuromolecular Med. 2013 Nov 23;16(2):292–307. doi: 10.1007/s12017-013-8277-3

Figure 8.

Figure 8

AS101 prevents VLA-4 positive cell migration to the central nervous system. (A-D) Quantification of brain infiltrates by flow cytometry. Whole brain mononuclear cells from sham (no disease), PBS (treatment control) and AS101 treated mice (n=5–10 per group) were removed on day 7, 14 and 21 post immunization and subjected to flow cytometry analysis for CD4(a), CD8(b) and VLA-4 (c,d). *p<0.05 versus Sham; **p<0.01 versus Sham; ##p < 0.01. (E) Representative spinal cords (n=5 mice per group) on day 14 post-immunization were stained with VLA-4 antibody. Bar = 500 µm.