Whole-brain T2, T2*, and T1 during NBAir, HBAir, and HBO (mean ± SEM, n shown at the bottom of each bar). Significant differences are indicated by the brackets with given uncorrected P-values. T1 and T2* data acquired during HBO without shielding were excluded from analysis due to artifacts. Furthermore, T2* HBO data were discarded in one animal with shielding in which the T2*-weighted images still had significant artifacts.